1n. a person opposed to the union of Upper with Lower Canada.
1822  We are aware that in regard to petitioners, the Anti-Unionists will have the greater number; but those who are friend to the Unions, the better arguments.
1848-1866  The Canadians of French descent, were almost to a man anti-unionists; those of British origin were, for the greatest part, unionists.
2n. a person opposed to Confederation.
1864  We caution anti-Unionists on the island to beware.
1868  He censured the course of the Administration as having been ill-advised and hasty; it had created great dissatisfaction in the Maritime Provinces causing strong friends of Union, to become anti-Unionists.